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BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells

In males, aging is accompanied by decline in serum testosterone levels due to impairment of testicular Leydig cells. The polycomb protein BMI1 has recently been identified as an anti-aging factor. In our previous study, BMI1 null mice showed decreased serum testosterone and Leydig cell population, e...

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Detalles Bibliográficos
Autores principales: Gao, Tingting, Lin, Meng, Shao, Binbin, Zhou, Qiao, Wang, Yufeng, Chen, Xia, Zhao, Dan, Dai, Xiuliang, Shen, Cong, Cheng, Hongbo, Yang, Shenmin, Li, Hong, Zheng, Bo, Zhong, Xingming, Yu, Jun, Chen, Li, Huang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469621/
https://www.ncbi.nlm.nih.gov/pubmed/32594840
http://dx.doi.org/10.1080/15384101.2020.1779471