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Ser(784) phosphorylation: a clinically relevant enhancer of VCP function in the DNA damage response

Valosin-containing protein (VCP) is essential for proteostasis during many cellular processes. However, it remains uncertain how its diverse functions are selectively regulated. We recently showed that DNA damage-induced Ser(784) phosphorylation specifically increases VCP function for the DNA damage...

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Detalles Bibliográficos
Autor principal: Shao, Jieya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469644/
https://www.ncbi.nlm.nih.gov/pubmed/32944647
http://dx.doi.org/10.1080/23723556.2020.1796179