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TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS

Macroautophagy/autophagy is an evolutionarily conserved cellular degradation and recycling process that is tightly regulated by external stimuli, diet, and stress. Our recent findings suggest that in C. elegans, a nutrient sensing pathway mediated by MTORC2 (mechanistic target of rapamycin kinase co...

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Detalles Bibliográficos
Autores principales: Heimbucher, Thomas, Qi, Wenjing, Baumeister, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469665/
https://www.ncbi.nlm.nih.gov/pubmed/32293958
http://dx.doi.org/10.1080/15548627.2020.1749368