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Report of the use of patient‐derived xenograft models in the development of anticancer drugs in Japan

Cell line‐derived xenograft (CDX) models created by implanting cancer cell lines into immunodeficient mice have contributed largely to the development of cancer drug therapies. However, cell lines often lose their original biological characteristics through many passages and cancer tissues in CDX mo...

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Detalles Bibliográficos
Autores principales: Tsumura, Ryo, Koga, Yoshikatsu, Hamada, Akinobu, Kuwata, Takeshi, Sasaki, Hiroki, Doi, Toshihiko, Aikawa, Katsuji, Ohashi, Akihiro, Katano, Ikumi, Ikarashi, Yoshinori, Ito, Mamoru, Ochiai, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469811/
https://www.ncbi.nlm.nih.gov/pubmed/32639672
http://dx.doi.org/10.1111/cas.14564