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FOXO1 inactivation induces cisplatin resistance in bladder cancer

We found that FOXO1‐shRNA sublines or FOXO1‐positive cells co–treated with a FOXO1 inhibitor were significantly more resistant to cisplatin treatment at pharmacological concentrations, compared with respective control sublines or those with mock treatment. Western blot demonstrated considerable incr...

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Detalles Bibliográficos
Autores principales: Ide, Hiroki, Goto, Takuro, Teramoto, Yuki, Mizushima, Taichi, Jiang, Guiyang, Nagata, Yujiro, Inoue, Satoshi, Baras, Alexander S., Kashiwagi, Eiji, Miyamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469822/
https://www.ncbi.nlm.nih.gov/pubmed/32678492
http://dx.doi.org/10.1111/cas.14557