Novel cucurmosin‐based immunotoxin targeting programmed cell death 1‐ligand 1 with high potency against human tumor in vitro and in vivo

Immunotoxins are Ab‐cytotoxin chimeric molecules with mighty cytotoxicity. Programmed cell death 1‐ligand 1 (PD‐L1), is a transmembrane protein expressed mainly in inflammatory tumor tissues and plays a pivotal role in immune escape and tumor progression. Although PD‐L1 immune checkpoint therapy has...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Caiyun, Xiong, Jiani, Lan, Yinxiang, Wu, Jingyu, Wang, Chengyan, Huang, Zhihong, Lin, Jizhen, Xie, Jieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469839/
https://www.ncbi.nlm.nih.gov/pubmed/32589330
http://dx.doi.org/10.1111/cas.14549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469839/
https://www.ncbi.nlm.nih.gov/pubmed/32589330
http://dx.doi.org/10.1111/cas.14549

Ejemplares similares