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Association of gBRCA1/2 mutation locations with ovarian cancer risk in Japanese patients from the CHARLOTTE study

Whether germline (g) breast cancer susceptibility gene (BRCA) mutations are located within or outside the ovarian cancer cluster region (OCCR) (1380‐4062 bp for gBRCA1, and between 3249‐5681 bp and 6645‐7471 bp for gBRCA2) may influence risk variations for ovarian cancers. This ad hoc analysis of th...

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Detalles Bibliográficos
Autores principales: Yoshihara, Kosuke, Enomoto, Takayuki, Aoki, Daisuke, Watanabe, Yoh, Kigawa, Junzo, Takeshima, Nobuhiro, Inomata, Hyoe, Hattori, Kana, Jinushi, Masahisa, Tsuda, Hitoshi, Sugiyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469841/
https://www.ncbi.nlm.nih.gov/pubmed/32495382
http://dx.doi.org/10.1111/cas.14513