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Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study

Epigenome-wide studies of methylation in children support a role for epigenetic mechanisms in asthma; however, studies in adults are rare and few have examined non-atopic asthma. We conducted the largest epigenome-wide association study (EWAS) of blood DNA methylation in adults in relation to non-at...

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Detalles Bibliográficos
Autores principales: Hoang, Thanh T., Sikdar, Sinjini, Xu, Cheng-Jian, Lee, Mi Kyeong, Cardwell, Jonathan, Forno, Erick, Imboden, Medea, Jeong, Ayoung, Madore, Anne-Marie, Qi, Cancan, Wang, Tianyuan, Bennett, Brian D., Ward, James M., Parks, Christine G., Beane-Freeman, Laura E., King, Debra, Motsinger-Reif, Alison, Umbach, David M., Wyss, Annah B., Schwartz, David A., Celedón, Juan C., Laprise, Catherine, Ober, Carole, Probst-Hensch, Nicole, Yang, Ivana V., Koppelman, Gerard H., London, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469973/
https://www.ncbi.nlm.nih.gov/pubmed/32381493
http://dx.doi.org/10.1183/13993003.00217-2020