Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors

A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhibitory activity against cancer cell lines represen...

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Detalles Bibliográficos
Autores principales: Sardaru, Monica-Cornelia, Craciun, Anda Mihaela, Al Matarneh, Cristina-Maria, Sandu, Isabela Andreea, Amarandi, Roxana Maria, Popovici, Lacramioara, Ciobanu, Catalina Ionica, Peptanariu, Dragos, Pinteala, Mariana, Mangalagiu, Ionel I., Danac, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470029/
https://www.ncbi.nlm.nih.gov/pubmed/32752898
http://dx.doi.org/10.1080/14756366.2020.1801671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470029/
https://www.ncbi.nlm.nih.gov/pubmed/32752898
http://dx.doi.org/10.1080/14756366.2020.1801671

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