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High-resolution structure of the alcohol dehydrogenase domain of the bifunctional bacterial enzyme AdhE

The bifunctional alcohol/aldehyde dehydrogenase (AdhE) comprises both an N-terminal aldehyde dehydrogenase (AldDH) and a C-terminal alcohol dehydrogenase (ADH). In vivo, full-length AdhE oligomerizes into long oligomers known as spirosomes. However, structural analysis of AdhE is challenging owing t...

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Detalles Bibliográficos
Autores principales: Azmi, Liyana, Bragginton, Eilis C., Cadby, Ian T., Byron, Olwyn, Roe, Andrew J., Lovering, Andrew L., Gabrielsen, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470043/
https://www.ncbi.nlm.nih.gov/pubmed/32880589
http://dx.doi.org/10.1107/S2053230X20010237