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Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents
Pancreatic cancer (PC) is one of the deadliest carcinomas and in most cases, which are diagnosed with locally advanced or metastatic disease, current therapeutic options are highly unsatisfactory. Based on the anti-proliferative effects shown by nitroxoline, an old urinary antibacterial agent, we ex...
Autores principales: | Veschi, Serena, Carradori, Simone, De Lellis, Laura, Florio, Rosalba, Brocco, Davide, Secci, Daniela, Guglielmi, Paolo, Spano, Mattia, Sobolev, Anatoly P., Cama, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470072/ https://www.ncbi.nlm.nih.gov/pubmed/32588672 http://dx.doi.org/10.1080/14756366.2020.1780228 |
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