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Inhibitory activity against carbonic anhydrase IX and XII as a candidate selection criterion in the development of new anticancer agents

Analysis of the literature data reveals that while inhibition of cancer-related carbonic anhydrase IX and XII isoforms continues to be an important enrichment factor for designing anticancer agent development libraries, exclusive reliance on the in vitro inhibition of these two recombinant isozymes...

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Detalles Bibliográficos
Autores principales: Krasavin, Mikhail, Kalinin, Stanislav, Sharonova, Tatiana, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470080/
https://www.ncbi.nlm.nih.gov/pubmed/32746643
http://dx.doi.org/10.1080/14756366.2020.1801674