Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison

In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, (1)H-NMR, (13)C-NMR, 2 D-NMR and HRMS spectroscopic methods. Amon...

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Detalles Bibliográficos
Autores principales: Acar Çevik, Ulviye, Sağlık, Begüm Nurpelin, Osmaniye, Derya, Levent, Serkan, Kaya Çavuşoğlu, Betül, Karaduman, Abdullah Burak, Atlı Eklioğlu, Özlem, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470102/
https://www.ncbi.nlm.nih.gov/pubmed/32811204
http://dx.doi.org/10.1080/14756366.2020.1806831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470102/
https://www.ncbi.nlm.nih.gov/pubmed/32811204
http://dx.doi.org/10.1080/14756366.2020.1806831

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