Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights

Human health in the current medical era is facing numerous challenges, especially cancer. So, the therapeutic arsenal for cancer should be unremittingly enriched with novel small molecules that selectively target tumour cells with minimal toxicity towards normal cells. In this context, herein a new...

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Detalles Bibliográficos
Autores principales: Sabt, Ahmed, Eldehna, Wagdy M., Al-Warhi, Tarfah, Alotaibi, Ohoud J., Elaasser, Mahmoud M., Suliman, Howayda, Abdel-Aziz, Hatem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470104/
https://www.ncbi.nlm.nih.gov/pubmed/32781872
http://dx.doi.org/10.1080/14756366.2020.1806259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470104/
https://www.ncbi.nlm.nih.gov/pubmed/32781872
http://dx.doi.org/10.1080/14756366.2020.1806259

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