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Co-delivery of doxorubicin and paclitaxel by reduction/pH dual responsive nanocarriers for osteosarcoma therapy

Nanoparticle-based drug delivery system offers a promising platform for combination cancer therapy. However, the inefficient drug release in cells reduces the therapeutic efficacy of cancer nanomedicines. Herein, a PEGylated poly(α-lipoic acid) copolymer (mPEG-PαLA) was prepared and used as a reduct...

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Detalles Bibliográficos
Autores principales: Li, Yongshuang, Hou, Hao, Zhang, Peng, Zhang, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470123/
https://www.ncbi.nlm.nih.gov/pubmed/32633576
http://dx.doi.org/10.1080/10717544.2020.1785049