Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5 position of isatin core exhibited better results c...

Descripción completa

Detalles Bibliográficos
Autores principales: Firoozpour, Loghman, Gao, Lixin, Moghimi, Setareh, Pasalar, Parvin, Davoodi, Jamshid, Wang, Ming-Wei, Rezaei, Zahra, Dadgar, Armin, Yahyavi, Hoda, Amanlou, Massoud, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470124/
https://www.ncbi.nlm.nih.gov/pubmed/32842789
http://dx.doi.org/10.1080/14756366.2020.1809388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470124/
https://www.ncbi.nlm.nih.gov/pubmed/32842789
http://dx.doi.org/10.1080/14756366.2020.1809388

Ejemplares similares