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Functional differences between protamine preparations for the transfection of mRNA

Protamine is a natural cationic peptide mixture used as a drug for the neutralization of heparin and in formulations of slow-release insulin. In addition, Protamine can be used for the stabilization and delivery of nucleic acids (antisense, small interfering RNA (siRNA), immunostimulatory nucleic ac...

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Detalles Bibliográficos
Autores principales: Jarzebska, Natalia Teresa, Lauchli, Severin, Iselin, Christoph, French, Lars E, Johansen, Pal, Guenova, Emmanuella, Kündig, Thomas M, Pascolo, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470126/
https://www.ncbi.nlm.nih.gov/pubmed/32804028
http://dx.doi.org/10.1080/10717544.2020.1790692