Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress

CONTEXT: Ursolic acid (UA), a natural product, shows a broad spectrum of anticancer effects. However, the poor bioavailability and efficacy of UA limit its clinical application. OBJECTIVE: We developed novel analogues of UA with enhanced antitumor activities by the extensive chemical modification of...

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Detalles Bibliográficos
Autores principales: Gou, Wenfeng, Luo, Na, Wei, Huiqiang, Wu, Hongying, Yu, Xiaojun, Duan, Yuqing, Bi, Changfen, Ning, Hongxin, Hou, Wenbin, Li, Yiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470152/
https://www.ncbi.nlm.nih.gov/pubmed/32726164
http://dx.doi.org/10.1080/13880209.2020.1794013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470152/
https://www.ncbi.nlm.nih.gov/pubmed/32726164
http://dx.doi.org/10.1080/13880209.2020.1794013

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