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Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress
CONTEXT: Ursolic acid (UA), a natural product, shows a broad spectrum of anticancer effects. However, the poor bioavailability and efficacy of UA limit its clinical application. OBJECTIVE: We developed novel analogues of UA with enhanced antitumor activities by the extensive chemical modification of...
Autores principales: | Gou, Wenfeng, Luo, Na, Wei, Huiqiang, Wu, Hongying, Yu, Xiaojun, Duan, Yuqing, Bi, Changfen, Ning, Hongxin, Hou, Wenbin, Li, Yiliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470152/ https://www.ncbi.nlm.nih.gov/pubmed/32726164 http://dx.doi.org/10.1080/13880209.2020.1794013 |
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