Curcumin attenuates renal interstitial fibrosis of obstructive nephropathy by suppressing epithelial-mesenchymal transition through inhibition of the TLR4/NF-кB and PI3K/AKT signalling pathways

CONTEXT: Renal interstitial fibrosis (RIF) is characterized by the accumulation of inflammatory cytokines and epithelial-mesenchymal transition (EMT). Curcumin exerts antifibrogenic, anti-inflammatory and antiproliferative effects. OBJECTIVE: To explore the mechanisms underlying the effects of curcu...

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Detalles Bibliográficos
Autores principales: Wang, Zhaohui, Chen, Zhi, Li, Bingsheng, Zhang, Bo, Du, Yongchao, Liu, Yuhang, He, Yao, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470153/
https://www.ncbi.nlm.nih.gov/pubmed/32866059
http://dx.doi.org/10.1080/13880209.2020.1809462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470153/
https://www.ncbi.nlm.nih.gov/pubmed/32866059
http://dx.doi.org/10.1080/13880209.2020.1809462

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