Mechanical stretching of pulmonary vein stimulates matrix metalloproteinase-9 and transforming growth factor-β1 through stretch-activated channel/MAPK pathways in pulmonary hypertension due to left heart disease model rats

Pulmonary hypertension due to left heart disease (PH-LHD) is a momentous pulmonary hypertension disease, and left heart disease is the most familiar cause. Mechanical stretching may be a crucial cause of vascular remodeling. While, the underlining mechanism of mechanical stretching-induced in remode...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Huang, Wenhui, Liu, Hongjin, Zheng, Yihan, Liao, Lianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470280/
https://www.ncbi.nlm.nih.gov/pubmed/32881898
http://dx.doi.org/10.1371/journal.pone.0235824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470280/
https://www.ncbi.nlm.nih.gov/pubmed/32881898
http://dx.doi.org/10.1371/journal.pone.0235824

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