Brefeldin A and Cytochalasin B reduce dengue virus replication in cell cultures but do not protect mice against viral challenge

BACKGROUND: Dengue is an emerging arboviral disease caused by dengue virus (DENV). DENV belongs to the family Flaviviridae and genus Flavivirus. No specific anti-DENV drugs are currently available. METHODS: We investigated the antiviral activity of Brefeldin A (BFA) and Cytochalasin B (CB) against t...

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Detalles Bibliográficos
Autores principales: Farias, Kleber Juvenal Silva, Machado, Paula Renata Lima, de Almeida Júnior, Renato Ferreira, Lopes da Fonseca, Benedito Antônio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470301/
https://www.ncbi.nlm.nih.gov/pubmed/32974532
http://dx.doi.org/10.1099/acmi.0.000041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470301/
https://www.ncbi.nlm.nih.gov/pubmed/32974532
http://dx.doi.org/10.1099/acmi.0.000041

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