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Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas

The prognosis for patients with glioblastoma (GB) remains grim. Concurrent temozolomide (TMZ) radiation—the cornerstone of glioma control—extends the overall median survival of GB patients by only a few months over radiotherapy alone. While these survival gains could be partly attributed to radiosen...

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Detalles Bibliográficos
Autores principales: Minea, Radu O., Duc, Tuan Cao, Swenson, Stephen D., Cho, Hee-Yeon, Huang, Mickey, Hartman, Hannah, Hofman, Florence M., Schönthal, Axel H., Chen, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470340/
https://www.ncbi.nlm.nih.gov/pubmed/32881880
http://dx.doi.org/10.1371/journal.pone.0238238