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Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells

The androgen receptor (AR) is activated in patients with castration resistant prostate cancer (CRPC) despite low circulating levels of androgen, suggesting that intracellular signaling pathways and non-androgenic factors may contribute to AR activation. Many G-protein coupled receptors (GPCR) and th...

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Detalles Bibliográficos
Autores principales: Singh, Julie Pratibha, Dagar, Manisha, Dagar, Gunjan, Kumar, Sudhir, Rawal, Sudhir, Sharma, Ravi Datta, Tyagi, Rakesh Kumar, Bagchi, Gargi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470385/
https://www.ncbi.nlm.nih.gov/pubmed/32881870
http://dx.doi.org/10.1371/journal.pone.0226056