Cargando…
Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells
The androgen receptor (AR) is activated in patients with castration resistant prostate cancer (CRPC) despite low circulating levels of androgen, suggesting that intracellular signaling pathways and non-androgenic factors may contribute to AR activation. Many G-protein coupled receptors (GPCR) and th...
Autores principales: | Singh, Julie Pratibha, Dagar, Manisha, Dagar, Gunjan, Kumar, Sudhir, Rawal, Sudhir, Sharma, Ravi Datta, Tyagi, Rakesh Kumar, Bagchi, Gargi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470385/ https://www.ncbi.nlm.nih.gov/pubmed/32881870 http://dx.doi.org/10.1371/journal.pone.0226056 |
Ejemplares similares
-
Adhesion GPCR GPR56 Expression Profiling in Human Tissues
por: Kaiser, Fyn, et al.
Publicado: (2021) -
The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα(12/13) and RhoA
por: Ackerman, Sarah D., et al.
Publicado: (2015) -
Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands
por: Salzman, Gabriel S., et al.
Publicado: (2020) -
The Orphan Adhesion-GPCR GPR126 Is Required for Embryonic Development in the Mouse
por: Waller-Evans, Helen, et al.
Publicado: (2010) -
Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion
por: Chatterjee, Treena, et al.
Publicado: (2021)