Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation

Synthetic lethality is a lethal phenomenon in which the occurrence of a single genetic event is tolerable for cell survival, whereas the co-occurrence of multiple genetic events results in cell death. The main obstacle for synthetic lethality lies in the tumor biology heterogeneity and complexity, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Topatana, Win, Juengpanich, Sarun, Li, Shijie, Cao, Jiasheng, Hu, Jiahao, Lee, Jiyoung, Suliyanto, Kenneth, Ma, Diana, Zhang, Bin, Chen, Mingyu, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470446/
https://www.ncbi.nlm.nih.gov/pubmed/32883316
http://dx.doi.org/10.1186/s13045-020-00956-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470446/
https://www.ncbi.nlm.nih.gov/pubmed/32883316
http://dx.doi.org/10.1186/s13045-020-00956-5

Ejemplares similares