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Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection

Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19. Because human angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV-2, mice expressing the human ACE2 gene have shown promise as a potential model for COVID-19. Five mice fro...

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Detalles Bibliográficos
Autores principales: Moreau, Gregory Brett, Burgess, Stacey L., Sturek, Jeffrey M., Donlan, Alexandra N., Petri, William A., Mann, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470527/
https://www.ncbi.nlm.nih.gov/pubmed/32723427
http://dx.doi.org/10.4269/ajtmh.20-0762