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Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection
Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19. Because human angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV-2, mice expressing the human ACE2 gene have shown promise as a potential model for COVID-19. Five mice fro...
Autores principales: | Moreau, Gregory Brett, Burgess, Stacey L., Sturek, Jeffrey M., Donlan, Alexandra N., Petri, William A., Mann, Barbara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470527/ https://www.ncbi.nlm.nih.gov/pubmed/32723427 http://dx.doi.org/10.4269/ajtmh.20-0762 |
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