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Paving the Road for RNA Therapeutics

Therapeutic RNA molecules possess high potential for treating medical conditions if they can successfully reach the target cell upon administration. However, unmodified RNA molecules are rapidly degraded and cleared from the circulation. In addition, their large size and negative charge complicates...

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Detalles Bibliográficos
Autores principales: Dammes, Niels, Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470715/
https://www.ncbi.nlm.nih.gov/pubmed/32893005
http://dx.doi.org/10.1016/j.tips.2020.08.004