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A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study

Genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants associated with various phenotypes, but together they explain only a fraction of heritability, suggesting many variants have yet to be discovered. Recently it has been recognized that incorporat...

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Detalles Bibliográficos
Autores principales: Dong, Xinyuan, Su, Yu-Ru, Barfield, Richard, Bien, Stephanie A., He, Qianchuan, Harrison, Tabitha A., Huyghe, Jeroen R., Keku, Temitope O., Lindor, Noralane M., Schafmayer, Clemens, Chan, Andrew T., Gruber, Stephen B., Jenkins, Mark A., Kooperberg, Charles, Peters, Ulrike, Hsu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470748/
https://www.ncbi.nlm.nih.gov/pubmed/32833970
http://dx.doi.org/10.1371/journal.pgen.1008947