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A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study
Genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants associated with various phenotypes, but together they explain only a fraction of heritability, suggesting many variants have yet to be discovered. Recently it has been recognized that incorporat...
Autores principales: | Dong, Xinyuan, Su, Yu-Ru, Barfield, Richard, Bien, Stephanie A., He, Qianchuan, Harrison, Tabitha A., Huyghe, Jeroen R., Keku, Temitope O., Lindor, Noralane M., Schafmayer, Clemens, Chan, Andrew T., Gruber, Stephen B., Jenkins, Mark A., Kooperberg, Charles, Peters, Ulrike, Hsu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470748/ https://www.ncbi.nlm.nih.gov/pubmed/32833970 http://dx.doi.org/10.1371/journal.pgen.1008947 |
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