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A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression

Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction, and eventual organ failure. Therefore, the development of effective antifibrotic drugs is urgently required. IMB-S7 is novel biphenyl compound derived from bifendate (biphenyldicarboxylate) that...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Zhao, Shuang-shuang, Zhang, Yi-xuan, Wang, Yu-cheng, Shao, Rong-guang, Wang, Ju-xian, He, Hong-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470799/
https://www.ncbi.nlm.nih.gov/pubmed/31932644
http://dx.doi.org/10.1038/s41401-019-0325-6