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RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination
RNF6, a RING-type ubiquitin ligase, has been identified as an oncogene in various cancers but its role in multiple myeloma (MM) remains elusive. In the present study we first showed that the expression levels of RNF6 in MM were significantly elevated compared with the bone marrow cells of healthy do...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470801/ https://www.ncbi.nlm.nih.gov/pubmed/31645658 http://dx.doi.org/10.1038/s41401-019-0309-6 |