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RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination

RNF6, a RING-type ubiquitin ligase, has been identified as an oncogene in various cancers but its role in multiple myeloma (MM) remains elusive. In the present study we first showed that the expression levels of RNF6 in MM were significantly elevated compared with the bone marrow cells of healthy do...

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Detalles Bibliográficos
Autores principales: Ren, Ying, Xu, Xin, Mao, Chen-yu, Han, Kun-kun, Xu, Yu-jia, Cao, Bi-yin, Zhang, Zu-bin, Sethi, Gautam, Tang, Xiao-wen, Mao, Xin-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470801/
https://www.ncbi.nlm.nih.gov/pubmed/31645658
http://dx.doi.org/10.1038/s41401-019-0309-6