Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway

Osteocalcin, expressed in osteoblasts of the bone marrow, undergoes post-translational carboxylation and deposits in mineralized bone matrix. A portion of osteocalcin remains uncarboxylated (uncarboxylated osteocalcin, GluOC) that is released into blood where it functions as a hormone to regulate in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiao-lin, Wang, Ya-nan, Ma, Lu-yao, Liu, Zhong-sheng, Ye, Fei, Yang, Jian-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470804/
https://www.ncbi.nlm.nih.gov/pubmed/31659239
http://dx.doi.org/10.1038/s41401-019-0311-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470804/
https://www.ncbi.nlm.nih.gov/pubmed/31659239
http://dx.doi.org/10.1038/s41401-019-0311-z

Ejemplares similares