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Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway

Osteocalcin, expressed in osteoblasts of the bone marrow, undergoes post-translational carboxylation and deposits in mineralized bone matrix. A portion of osteocalcin remains uncarboxylated (uncarboxylated osteocalcin, GluOC) that is released into blood where it functions as a hormone to regulate in...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiao-lin, Wang, Ya-nan, Ma, Lu-yao, Liu, Zhong-sheng, Ye, Fei, Yang, Jian-hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470804/ https://www.ncbi.nlm.nih.gov/pubmed/31659239 http://dx.doi.org/10.1038/s41401-019-0311-z

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