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Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury

Melatonin receptors (MTs) are potential drug targets for stroke therapy. Ramelteon is a selective melatonin receptor agonist used to treat insomnia. In this study we investigated whether ramelteon could attenuate cerebral ischemia in mice. Acute focal cerebral ischemia was induced in mice via middle...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-li, Lu, Shou-sheng, Liu, Meng-ru, Tang, Wei-dong, Chen, Jun-zi, Zheng, Yan-rong, Ahsan, Anil, Cao, Ming, Jiang, Lei, Hu, Wei-wei, Wu, Jia-ying, Chen, Zhong, Zhang, Xiang-nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470806/
https://www.ncbi.nlm.nih.gov/pubmed/32107468
http://dx.doi.org/10.1038/s41401-020-0361-2