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Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain
Paclitaxel-induced neuropathic pain (PINP) is refractory to currently used analgesics. Previous studies show a pivotal role of oxidative stress in PINP. Because the nuclear factor erythroid-2-related factor 2 (Nrf2) has been considered as the critical regulator of endogenous antioxidant defense, we...
Autores principales: | Zhou, Ya-qun, Liu, Dai-qiang, Chen, Shu-ping, Chen, Nan, Sun, Jia, Wang, Xiao-mei, Cao, Fei, Tian, Yu-ke, Ye, Da-wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470811/ https://www.ncbi.nlm.nih.gov/pubmed/32203087 http://dx.doi.org/10.1038/s41401-020-0394-6 |
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