Co-expression analysis reveals interpretable gene modules controlled by trans-acting genetic variants

Understanding the causal processes that contribute to disease onset and progression is essential for developing novel therapies. Although trans-acting expression quantitative trait loci (trans-eQTLs) can directly reveal cellular processes modulated by disease variants, detecting trans-eQTLs remains...

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Detalles Bibliográficos
Autores principales: Kolberg, Liis, Kerimov, Nurlan, Peterson, Hedi, Alasoo, Kaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470823/
https://www.ncbi.nlm.nih.gov/pubmed/32880574
http://dx.doi.org/10.7554/eLife.58705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470823/
https://www.ncbi.nlm.nih.gov/pubmed/32880574
http://dx.doi.org/10.7554/eLife.58705

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