The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

Dose-limiting toxicities for cisplatin administration, including ototoxicity and nephrotoxicity, impact the clinical utility of this effective chemotherapy agent and lead to lifelong complications, particularly in pediatric cancer survivors. Using a two-pronged drug screen employing the zebrafish la...

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Detalles Bibliográficos
Autores principales: Wertman, Jaime N, Melong, Nicole, Stoyek, Matthew R, Piccolo, Olivia, Langley, Stewart, Orr, Benno, Steele, Shelby L, Razaghi, Babak, Berman, Jason N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470826/
https://www.ncbi.nlm.nih.gov/pubmed/32720645
http://dx.doi.org/10.7554/eLife.56235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470826/
https://www.ncbi.nlm.nih.gov/pubmed/32720645
http://dx.doi.org/10.7554/eLife.56235

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