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The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model
Dose-limiting toxicities for cisplatin administration, including ototoxicity and nephrotoxicity, impact the clinical utility of this effective chemotherapy agent and lead to lifelong complications, particularly in pediatric cancer survivors. Using a two-pronged drug screen employing the zebrafish la...
Autores principales: | Wertman, Jaime N, Melong, Nicole, Stoyek, Matthew R, Piccolo, Olivia, Langley, Stewart, Orr, Benno, Steele, Shelby L, Razaghi, Babak, Berman, Jason N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470826/ https://www.ncbi.nlm.nih.gov/pubmed/32720645 http://dx.doi.org/10.7554/eLife.56235 |
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