Upregulation of TRPM3 in nociceptors innervating inflamed tissue

Genetic ablation or pharmacological inhibition of the heat-activated cation channel TRPM3 alleviates inflammatory heat hyperalgesia, but the underlying mechanisms are unknown. We induced unilateral inflammation of the hind paw in mice, and directly compared expression and function of TRPM3 and two o...

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Detalles Bibliográficos
Autores principales: Mulier, Marie, Van Ranst, Nele, Corthout, Nikky, Munck, Sebastian, Vanden Berghe, Pieter, Vriens, Joris, Voets, Thomas, Moilanen, Lauri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470828/
https://www.ncbi.nlm.nih.gov/pubmed/32880575
http://dx.doi.org/10.7554/eLife.61103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470828/
https://www.ncbi.nlm.nih.gov/pubmed/32880575
http://dx.doi.org/10.7554/eLife.61103

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