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Protein tyrosine phosphatase L1 represses endothelial-mesenchymal transition by inhibiting IL-1β/NF-κB/Snail signaling

Endothelial–mesenchymal transition (EnMT) plays a pivotal role in various diseases, including pulmonary hypertension (PH), and transcription factors like Snail are key regulators of EnMT. In this study we investigated how these factors were regulated by PH risk factors (e.g. inflammation and hypoxia...

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Detalles Bibliográficos
Autores principales: Wei, Xiao-min, Wumaier, Gulinuer, Zhu, Ning, Dong, Liang, Li, Cheng-wei, Xia, Jing-wen, Zhang, You-zhi, Zhang, Peng, Zhang, Xiu-juan, Zhang, Yuan-yuan, Li, Sheng-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470836/
https://www.ncbi.nlm.nih.gov/pubmed/32152438
http://dx.doi.org/10.1038/s41401-020-0374-x