SGK1 mediates the hypotonic protective effect against H(2)O(2)-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway

Serum- and glucocorticoid-inducible kinease-1 (SGK1) is a serine/threonine kinase regulated by hypotonic stimuli, which is involved in regulation of cell cycle and apoptosis. Our previous study shows that activation of volume-regulated Cl(−) channels (VRCCs) protects rat basilar artery smooth muscle...

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Detalles Bibliográficos
Autores principales: Chen, Bao-yi, Huang, Cheng-cui, Lv, Xiao-fei, Zheng, Hua-qing, Zhang, Ya-juan, Sun, Lu, Wang, Guan-lei, Ma, Ming-ming, Guan, Yong-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470837/
https://www.ncbi.nlm.nih.gov/pubmed/32139897
http://dx.doi.org/10.1038/s41401-020-0357-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470837/
https://www.ncbi.nlm.nih.gov/pubmed/32139897
http://dx.doi.org/10.1038/s41401-020-0357-y

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