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Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein

Abnormal protein aggregation has been linked to many neurodegenerative diseases, including Parkinson’s disease (PD). The main pathological hallmark of PD is the formation of Lewy bodies (LBs) and Lewy neurites, both of which contain the presynaptic protein alpha-synuclein (α-syn). Under normal condi...

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Detalles Bibliográficos
Autores principales: Xu, Ming-ming, Ryan, Philip, Rudrawar, Santosh, Quinn, Ronald J, Zhang, Hai-yan, Mellick, George D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470848/
https://www.ncbi.nlm.nih.gov/pubmed/31586134
http://dx.doi.org/10.1038/s41401-019-0304-y