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Donepezil attenuates vascular dementia in rats through increasing BDNF induced by reducing HDAC6 nuclear translocation

Vascular dementia (VD) is the second most common dementia disease after Alzheimer’s diseases (AD) in the world. Donepezil is used to treat mild to moderate AD, and it has been shown to treat cognitive impairment and memory deficits caused by VD. However, the action mechanism of donepezil against VD...

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Detalles Bibliográficos
Autores principales: Jian, Wen-xuan, Zhang, Zhao, Zhan, Jia-hong, Chu, Shi-feng, Peng, Ye, Zhao, Ming, Wang, Qi, Chen, Nai-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470853/
https://www.ncbi.nlm.nih.gov/pubmed/31913348
http://dx.doi.org/10.1038/s41401-019-0334-5