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Donepezil attenuates vascular dementia in rats through increasing BDNF induced by reducing HDAC6 nuclear translocation
Vascular dementia (VD) is the second most common dementia disease after Alzheimer’s diseases (AD) in the world. Donepezil is used to treat mild to moderate AD, and it has been shown to treat cognitive impairment and memory deficits caused by VD. However, the action mechanism of donepezil against VD...
Autores principales: | Jian, Wen-xuan, Zhang, Zhao, Zhan, Jia-hong, Chu, Shi-feng, Peng, Ye, Zhao, Ming, Wang, Qi, Chen, Nai-hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470853/ https://www.ncbi.nlm.nih.gov/pubmed/31913348 http://dx.doi.org/10.1038/s41401-019-0334-5 |
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