Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats

Accumulating evidence suggests that KNDy neurons located in the hypothalamic arcuate nucleus (ARC), which are reported to express kisspeptin, neurokinin B, and dynorphin A, are indispensable for the gonadotropin-releasing hormone (GnRH) pulse generation that results in rhythmic GnRH secretion. The a...

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Detalles Bibliográficos
Autores principales: SASAKI, Takuya, SONODA, Tomoya, TATEBAYASHI, Ryoki, KITAGAWA, Yuri, OISHI, Shinya, YAMAMOTO, Koki, FUJII, Nobutaka, INOUE, Naoko, UENOYAMA, Yoshihisa, TSUKAMURA, Hiroko, MAEDA, Kei-ichiro, MATSUDA, Fuko, MORITA, Yasuhiro, MATSUYAMA, Shuichi, OHKURA, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470901/
https://www.ncbi.nlm.nih.gov/pubmed/32281549
http://dx.doi.org/10.1262/jrd.2019-145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470901/
https://www.ncbi.nlm.nih.gov/pubmed/32281549
http://dx.doi.org/10.1262/jrd.2019-145

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