Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine

The addictive component of tobacco, nicotine, acts via nicotinic acetylcholine receptors (nAChRs). The β2 subunit-containing nAChRs (β2-nAChRs) play a crucial role in the rewarding properties of nicotine and are particularly densely expressed in the mesolimbic dopamine (DA) system. Specifically, nAC...

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Detalles Bibliográficos
Autores principales: Morozova, Ekaterina, Faure, Philippe, Gutkin, Boris, Lapish, Christoper, Kuznetsov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470928/
https://www.ncbi.nlm.nih.gov/pubmed/32737187
http://dx.doi.org/10.1523/ENEURO.0418-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470928/
https://www.ncbi.nlm.nih.gov/pubmed/32737187
http://dx.doi.org/10.1523/ENEURO.0418-19.2020

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