MtDNA sequence features associated with ‘selfish genomes’ predict tissue-specific segregation and reversion

Mitochondrial DNA (mtDNA) encodes cellular machinery vital for cell and organism survival. Mutations, genetic manipulation, and gene therapies may produce cells where different types of mtDNA coexist in admixed populations. In these admixtures, one mtDNA type is often observed to proliferate over an...

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Detalles Bibliográficos
Autores principales: Røyrvik, Ellen C, Johnston, Iain G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470939/
https://www.ncbi.nlm.nih.gov/pubmed/32716035
http://dx.doi.org/10.1093/nar/gkaa622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470939/
https://www.ncbi.nlm.nih.gov/pubmed/32716035
http://dx.doi.org/10.1093/nar/gkaa622

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