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MtDNA sequence features associated with ‘selfish genomes’ predict tissue-specific segregation and reversion
Mitochondrial DNA (mtDNA) encodes cellular machinery vital for cell and organism survival. Mutations, genetic manipulation, and gene therapies may produce cells where different types of mtDNA coexist in admixed populations. In these admixtures, one mtDNA type is often observed to proliferate over an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470939/ https://www.ncbi.nlm.nih.gov/pubmed/32716035 http://dx.doi.org/10.1093/nar/gkaa622 |